Many towns on the western plains were built along the route of the railroad as it was constructed, but few grew to be as large and important as Laramie. It makes sense, then, that the center of the city would be the train depot.
The original depot, located in the northern area of town on 3rd Street, eventually expanded to include a hotel. When a fire swept through it, a new depot was built on Second Avenue near Garfield.
With the advent of the automobile, passenger train travel on the train diminished. Today, the depot is open to the public as a museum dedicated to those early railroad days.